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However, side effects can be a concern for older adults or people who have health problems.

First-generation antihistamines may make you feel sleepy.

Two types of OTC antihistamines are available: first-generation and second-generation. First-generation antihistamines are sometimes used in OTC cold medicines.

When your body is exposed to allergens (something that triggers an allergy), it makes histamines. This can cause itching, sneezing, runny nose, and watery eyes.

Your system releases these chemicals to help get rid of the allergen. Antihistamines prevent histamines from attaching to your cells and causing symptoms.

These were some of the first antihistamines scientists developed. They also work in the part of the brain that controls nausea and vomiting. One of the most common side effects of first-generation antihistamines is feeling sleepy.

It is a good idea to treat just the symptoms that you have.

OTC means you can buy them at a store, without a prescription from your doctor.

They are available in pills or liquids, nasal sprays or gels, and eyedrops.

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